introduction in order to treat uveal melanoma , first, radioactive seeds are laid on a silicone- made substance which is called silastic after that they are inserted in the plaque, and finally, this plaque containing silicone-made substance is stitched to the sclera surface. the dose gradient within the tumor and healthy tissues can be varied due to changing the silastic thickness between scler...

Introduction: Brachytherapy is one type of internal radiation therapy where radiation sources, which are usually encapsulated, are placed as close as possible to the tumor site or inside the patient's body. In this technique, it is important to determine dose distribution around the brachytherapy capsule to create optimal treatment plant. In this way, dosimetric parameters are...

The calibration of a liquid I-125 source in an older standard dose calibration system is presented. The calibration factor agrees well with factors established by the NIST for newer dose calibration systems. The determination of the source activity is necessary to accurately calculate the time required to deliver the prescribed dose.

Introduction In order to treat uveal Melanoma , first, radioactive seeds are laid on a silicone- made substance which is called Silastic after that they are inserted in the plaque, and finally, this plaque containing silicone-made substance is stitched to the sclera surface. The dose gradient within the tumor and healthy tissues can be varied due to changing the Silastic thickness between scler...

Early-stage prostate cancer is widely treated by iodine-125 (I-125) seed implantation. While quality assurance methods are in place to assure consistency in I-125 seed source strength, current methods involve the breaking of the sterilization package, raising issues concerning sterility and time limitations. The purpose of this study was to develop a method of characterizing the total source st...

PURPOSE Low energy sources are routinely used in prostate brachytherapy. (125)I is one of the most commonly used sources. Low energy (131)Cs source was introduced recently as a brachytherapy source. The aim of this study is to compare dose distributions of (125)I, (103)Pd, and (131)Cs sources in interstitial brachytherapy of prostate. MATERIAL AND METHODS ProstaSeed (125)I brachytherapy sourc...

PURPOSE To improve tumor dose conformity and homogeneity for COMS plaque brachytherapy by investigating the dosimetric effects of varying component source ring radionuclides and source strengths. MATERIAL AND METHODS The MCNP5 Monte Carlo (MC) radiation transport code was used to simulate plaque heterogeneity-corrected dose distributions for individually-activated source rings of 14, 16 and 1...

PURPOSE To determine the relative dose rate distribution around the new (125)I brachytherapy source IsoSeed I25.S17plus and report results in a form suitable for clinical use. Results for the new source are also compared to corresponding results for other commercially available (125)I sources of similar design. MATERIAL AND METHODS Monte Carlo simulations were performed using the MCNP5 v.1.6 ...